I want to share a case of 2 years old twin baby girls, presented to me in Rehman Medical Institute suffering from severe type of anemia. Just because some states will allow it does not mean the chance for birth defects is any less in those states. During the consultation, you can also discuss with your doctor, what can do if you have a child or expecting a child with a hereditary disease, whether the disease can be treated and who might be able to help the child and the family. A single first-cousin marriage has a greater risk of birth defects than the offspring of non-cousin couples of only somewhere between 1–4% (non-cousin couples have about a 3% risk of birth defects). In this regard, the risk of birth defects in the offspring of first-cousin marriage is expected to increase sharply compared to non-consanguineous marriages particularly for rare autosomal recessive disease genes, because for common recessive conditions, there is a high chance that the abnormal gene may be carried by … The overall findings are in close agreement with a study published last year, based on a meta-analysis of 17 populations living in six countries. If the genetic defect that caused of any disease in the family is known, a gene test can determine whether or not an individual carries the defective gene. As of 2003, an average of 45% of married couples were related in the Arab world. Children born in marriages between first cousins have double the risk of congenital anomalies, a new UK study has found.1 Researchers followed 13 776 pregnancies in Bradford and found that 6.1% of children born to first cousins had congenital anomalies and that 98% of these children were born to people of Pakistani origin. It was estimated in 1960 that 0.2% of all marriages between Roman Catholics were between first or second cousins, but no more recent nationwide studies have been performed. A child of first cousins is more likely to have birth defects than two people who meet at ... Taiwan, North Korea and South Korea and the Philippines all have bans on first cousin marriage. Such conditions include metabolic diseases, skin diseases, blood diseases, psychiatric diseases, physical and mental development problems, as well as problems with hearing or vision. Disappointingly, the authors were unable to collect representative information on biraderi membership. Ruba and her first child, ... She says it was Inara's death that made her accept a link between her children's misfortunes and cousin marriage. The authors found that cousin marriages and maternal age were associated with a significant increase in risk of birth defects. Today marrying your first cousin is illegal in 24 US states. In fact, it is estimated thatas many as 80% of the marriages in human historyhave been between first or second cousins. This means babies born to couples who are blood relatives have more probabilities to develop a birth defect. Children born in marriages between first cousins have double the risk of congenital anomalies, a new UK study has found. Dr Muhammad Ali, a District Health Officer (DHO) at Charsadda's district hospital, says that first-cousin marriages result in children with genetic disorders. This possibility needs to be kept firmly in mind as transnational marriages between UK-born and Pakistani partners are still favoured by many families in the UK Pakistani community, including those who would have been counted in the study. Not being able to control for this division into genetic and sociocultural sub-communities seriously undermines the claim that 31% of congenital anomalies in the UK Pakistani population are solely due to marriage between first cousins. In my humble opinion it is less important, unless you provide better stats. My wife and I are first cousins. BMJ. In the Bradford Pakistani community, marriage between close family members is widely believed to offer significant benefits to the couple, who often have known each other from childhood, and to strengthen family ties. The risk of having a baby with birth defects, usually heart or nervous system problems, is still small but rises from 3% in the general Pakistani population to 6% among those married … In fact we all carry different genetic defects that can lead to diseases in ourselves or in our children. Though marriage between blood relatives increases the risk of genetic defects in offspring, the practice is banned in only three nations: the United States, ... Thirty-six percent of adults who had been born to first-cousin couples had been prescribed either an antidepressant or anti-anxiety drug. But many cultures encourage marriage between cousins, for a variety of reasons. These dangers are more in the first cousins. Through a combination of old prejudices and present-day conventional wisdom about inherited birth defects, first cousin marriage is seen by many as a little too … One of the problems in the debate is that many figures get bandied about but really good data on the health effects of first-cousin marriage is lacking. However, while marriage between first cousins doubles the risk of children being born with birth defects, the rate is still fairly low. In many of these cases, the health of the child is little affected. On 13 May 2014 the Conservative Muslim Forum held an event on the relationship between first cousin marriage and birth defects, and the policy implications. I would like to suggest married couples, if you are blood relatives and you already have one or more children with a debilitating disease or birth defect, then you must go for genetic consultation and counseling. 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